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Amine (NH2) functional microparticles may be used to physically adsorb biomolecules through ionic interaction, or they can be chemically functionalized for covalent coupling of biomolecules using a variety of bi-functional chemical coupling agents. The most frequently used coupling agents include glutaraldehyde and 1,4-butanediol diglycidyl ether.
For possible coupling chemistries and protocols we recommend you consult with the following reference: Hermanson, G.T. Bioconjugate Techniques, 2nd?Edition, Academic Press Inc. (2008)
