MagReSyn Protein A - 2ml ultra-capacity high performance magnetic microparticles

$352.00

SKU MR-PRA002 Category

Description

High capacity Protein A for affinity purification of antibodies and immunoprecipitation

MagReSyn Protein A microparticles contain covalently coupled Protein A for highly specific single-step purification of IgG to >95% purity from whole serum samples. Protein A is a ~56 kDa surface protein originally isolated from the cell wall of the bacterium Staphylococcus aureus and is widely used for highly specific purification of IgG antibodies and for immunoprecipitation experiments. Protein A has 5 immunoglobulin binding domains folded into a three-helix bundle and specifically binds the Fc region on the heavy chain of the IgG class of antibodies. More specifically, Protein A binds with high affinity to specific subclasses of human, rabbit, mouse, guinea pig, cat and pig IgG. It does not react with human IgG3, IgD or IgE, mouse IgM, IgA or IgE, or goat, koala and llama IgG. The high recombinant Protein A content of MagReSyn ensures a high immunoglobulin capacity allowing for experimental miniaturization.

Additional information

Weight 16 oz
Dimensions 12 × 3 × 17 in